Bipolar

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Originally published May 28, 2022
Updated occasionally


TrueHope brain directed multivitamin (50% average improvement to symptoms, much lower use of medications (74% average reduction (at 6 months), with a 2.55x increase to those taking no medication (22% to 56%), with those still on medication taking 54% less on average)
10% of patients had an adverse reaction to the multivitamin and got 25% worse symptoms (on average)
https://www.truehope.com/
(See drive)

Keto (see drive keto schizophrenia) Really helps (58% improvement)

NAC 2 grams a day (d = 1.04) and a chelated mineral and vitamin formula (d = 1.70)(TrueHope) helped bipolar depression
A chelated mineral formula (d = 0.83)(TrueHope), L-tryptophan (d = 1.47), magnesium (d = 1.44), folic acid (d = 0.40) all helped bipolar mania by that amount
(see drive for more data (meta analysis)) non schiz folder)

Insulin resistance plays a major role in bipolar disorder. Metformin, and lithium, both help with this. (43% improvement with metformin alone (18% placebo (or less)) (in those who had insulin resistance that was fixed by metformin))
(30% improvement mania (placebo group got worse mania (12%)) 56% improvement depression (27% placebo))

Bipolar list 
Fish oil helps (may help depression)
Choline
Inositol (helps with panic attacks for sure)

Carnivore diet (see drive carnivore) experimental treatment likely helps, bioaccumulation of nutrients in meat (combined with less alergens)

Helminths help (HDC) 95% effective, little side effects (sample size was only 5 people) (see drive)

Allergens may be the cause of your bipolar

(This article doesn't have data on lithium (likely helpful), or antipsychotics (likely less so). I will add this data (hopefully shortly)).

Please see the schizophrenia entry for more suggestions (as schizophrenia and bipolar have physiological similarities).


Bipolar currently costs the US economy 1.4% of total GDP (2023)






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