Arthritis
Originally published: Jan 11, 2025
Updated occasionally
Osteoarthritis:
1)Reducing odds of getting arthritis
Obesity
Sedentary behaviour
Diet
Inflammation
2)Dealing with arthritis
"Joint pain was measured on days 14, 28, and 56. Using a standard WOMAC score (a 24-question assessment of pain, stiffness, and physical limitations), those who took the krill oil, astaxanthin, and hyaluronic acid blend had:5
A progressive decrease in pain severity on each testing day,
Pain-free status in 25% of patients by day 14, and
Pain-free status in 63% of patients by day 56.
By day 56, controlling for the effect of placebo, the blend achieved a 55% reduction in WOMAC pain scores, outperforming the 35% reduction achieved by the glucosamine-chondroitin treatment.5
Another measure of joint pain, the patient-reported Visual Analogue Scale (VAS), showed:5
Progressive decrease in pain severity on each testing day, and
Pain-free status in an astonishing 68% of patients by day 56."
https://www.lifeextension.com/magazine/2025/2/joint-pain-enhanced-krill-oil
"In this study, 118 patients with mild to moderate joint discomfort were treated three times daily for 12 weeks with either 500 mg of glucosamine, 500 mg MSM, a combination of both, or an inactive placebo. The patients were evaluated at 0, 2, 4, 8, and 12 weeks. The study evaluated patients’ pain, inflammation, and swelling.
Glucosamine, MSM, and the combination of glucosamine and MSM improved the pain and swelling compared with placebo. After 12 weeks of treatment, the average pain score in the glucosamine-only group dropped from 1.74 to 0.65…a 63% reduction. In the MSM-only group, it fell from 1.53 to 0.74...a 52% reduction. However, in the group taking glucosamine and MSM, the average pain score dropped from 1.7 to 0.36…an astounding reduction of 79%! The researchers also found that the combination therapy had a faster effect on pain and inflammation than either glucosamine or MSM alone."
A progressive decrease in pain severity on each testing day,
Pain-free status in 25% of patients by day 14, and
Pain-free status in 63% of patients by day 56.
By day 56, controlling for the effect of placebo, the blend achieved a 55% reduction in WOMAC pain scores, outperforming the 35% reduction achieved by the glucosamine-chondroitin treatment.5
Another measure of joint pain, the patient-reported Visual Analogue Scale (VAS), showed:5
Progressive decrease in pain severity on each testing day, and
Pain-free status in an astonishing 68% of patients by day 56."
https://www.lifeextension.com/magazine/2025/2/joint-pain-enhanced-krill-oil
"In this study, 118 patients with mild to moderate joint discomfort were treated three times daily for 12 weeks with either 500 mg of glucosamine, 500 mg MSM, a combination of both, or an inactive placebo. The patients were evaluated at 0, 2, 4, 8, and 12 weeks. The study evaluated patients’ pain, inflammation, and swelling.
Glucosamine, MSM, and the combination of glucosamine and MSM improved the pain and swelling compared with placebo. After 12 weeks of treatment, the average pain score in the glucosamine-only group dropped from 1.74 to 0.65…a 63% reduction. In the MSM-only group, it fell from 1.53 to 0.74...a 52% reduction. However, in the group taking glucosamine and MSM, the average pain score dropped from 1.7 to 0.36…an astounding reduction of 79%! The researchers also found that the combination therapy had a faster effect on pain and inflammation than either glucosamine or MSM alone."
https://www.lifeextension.com/magazine/2004/ss/joints
"The results were impressive, with mean pain scores on the standardized "WOMAC" scale being reduced after 90 days by 33% in the UC-II® group, and only a more modest reduction of 14% in the glucosamine/chondroitin group.4 Similarly, pain scores on the visual analog scale (VAS) dropped by 40% as compared with just 15% in the glucosamine/chondroitin group. Equally importantly, the UC-II® group's scores declined continuously through the study, while the glucosamine/chondroitin group, after initial improvement, showed no further beneficial effects." (UC-II is a type of collagen)
"The results were impressive, with mean pain scores on the standardized "WOMAC" scale being reduced after 90 days by 33% in the UC-II® group, and only a more modest reduction of 14% in the glucosamine/chondroitin group.4 Similarly, pain scores on the visual analog scale (VAS) dropped by 40% as compared with just 15% in the glucosamine/chondroitin group. Equally importantly, the UC-II® group's scores declined continuously through the study, while the glucosamine/chondroitin group, after initial improvement, showed no further beneficial effects." (UC-II is a type of collagen)
https://www.lifeextension.com/magazine/2011/ss/rebuild-aging-joints
Tamarind and turmeric
"Results of the WOMAC scale were nearly as impressive, with the 400 mg group reporting a 38% reduction in pain, stiffness, and physical limitations, compared to 7% in the placebo group."
Tamarind and turmeric
"Results of the WOMAC scale were nearly as impressive, with the 400 mg group reporting a 38% reduction in pain, stiffness, and physical limitations, compared to 7% in the placebo group."
https://www.lifeextension.com/magazine/2022/6/reduce-joint-pain-improve-mobility
"Scientists examined the impact of cutch tree and white mulberry on the breakdown of proteoglycans, essential components of the cartilage matrix that cushions and lubricates joints. They found these two plant extracts reduced cartilage breakdown by 31%-54%, depending on the dose used.6 This demonstrated the mixture’s cartilage-protecting abilities in the laboratory model, which we’ve now seen echoed in the 2017 human study."
"Scientists examined the impact of cutch tree and white mulberry on the breakdown of proteoglycans, essential components of the cartilage matrix that cushions and lubricates joints. They found these two plant extracts reduced cartilage breakdown by 31%-54%, depending on the dose used.6 This demonstrated the mixture’s cartilage-protecting abilities in the laboratory model, which we’ve now seen echoed in the 2017 human study."
https://www.lifeextension.com/magazine/2018/5/plant-compounds-protect-joint-cartilage
Products:
#1 https://www.lifeextension.com/vitamins-supplements/item02238/arthromax-advanced-with-nt2-collagen-and-apresflex
#2 https://www.lifeextension.com/vitamins-supplements/item01600/krill-healthy-joint-formula
#3 https://www.lifeextension.com/vitamins-supplements/item02424/joint-mobility
Applying a comfrey cream or salve can reduce osteoarthritis pain by 50% (as opposed to 10-15% from a placebo), however it does not heal the underlying issue
Products:
#1 https://www.lifeextension.com/vitamins-supplements/item02238/arthromax-advanced-with-nt2-collagen-and-apresflex
#2 https://www.lifeextension.com/vitamins-supplements/item01600/krill-healthy-joint-formula
#3 https://www.lifeextension.com/vitamins-supplements/item02424/joint-mobility
Applying a comfrey cream or salve can reduce osteoarthritis pain by 50% (as opposed to 10-15% from a placebo), however it does not heal the underlying issue
Stem cells and PRP (need to research more)
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