Endometriosis
Originally published: Jan 14, 2025
Updated occasionally
"these investigators observed that more active women (≥42 MET hours/week)
had an 11% reduction of the risk for endometriosis. Considering the
physical activity performed 4 years before the diagnosis of
endometriosis, there was a 90% reduction of the risk for the disease
among patients who exercised 42 MET hours/week compared to those who
exercised only 3 MET hours/week.
Practice 2 to 4 hours per week of regular exercise decreases 65% chance of endometriosis
Avoidance of strenuous exercise during the menstruation is a preventive factor for endometriosis"
Yoga reduced pain by 47%, infertility by 35% (however 15% reduction in the non-yoga group) (endometriosis is a leading cause of infertility (0.5x lower odds of getting pregnant in a year))
"The pooled relative risk of endometriosis was 0.67 (95% CI: 0.53, 0.84) for each 5 kg/m2 increase in current body mass index"
"Compared with normal weight women, the pooled relative risk for obese
women was 0.89 (95% CI: 0.83, 0.96), which was lower than that for
overweight women (relative risk =0.97; 95% CI: 0.91, 1.05)." (Higher BMI is associated with lower risk of endometriosis)
"BMI was significantly lower in women with endometriosis than in controls (p < 0.001); this difference was confirmed when the analysis was restricted to subjects with normal BMI (18.50–24.99 kg/m2) (p = 0.002). 4.8% of control subjects and no woman with endometriosis were obese."
"those women in the highest fifth of long-chain omega-3 fatty acid
consumption were 22% less likely to be diagnosed with endometriosis
compared with those with the lowest fifth of intake [95% confidence
interval (CI) = 0.62–0.99; P-value, test for linear trend (Pt) = 0.03]. In addition, those in the highest quintile of trans-unsaturated fat intake were 48% more likely to be diagnosed with endometriosis (95% CI = 1.17–1.88; Pt = 0.001)."
"the study shows that women who ate more than two servings of red meat per
day had a 56% higher risk of developing endometriosis compared
with those who consumed less than one serving per week."
"50,000 international units of vitamin D every two weeks for 12 weeks significantly reduced self-reported pelvic pain."
Chamomile tea helps
Probiotics help
NAC helps
Resveratrol helps
7.2x risk if you have a first degree relative with endometriosis
For the association of risk of endometriosis and menstrual cycle length shorter than or equal to 27 days (SEQ27) or length longer than or equal to 29 days (LEQ29), the odds ratio was 1.22 (95% confidence interval [CI]: 1.05–1.43) and 0.68 (95% CI: 0.48–0.96), respectively.
Early menarche (< 12 years) was associated with a significant pooled risk of endometriosis with high heterogeneity (OR = 1.34, 95% CI 1.16-1.54, I2 = 72.0%). Stratified analysis showed that this risk was increased in studies started after 2000 (OR = 1.62, 95% CI 0.96-1.35, I2 = 74.4%), compared to those before 2000 (OR = 1.13, 95% CI 1.16-1.54, I2 = 40.7%); additionally, this risk was higher in low-income countries (OR = 2.11, 95% CI 1.55-2.87, I2 = 0%) than in other countries (OR = 1.25, 95% CI 1.09-1.43, I2 = 70.6%).
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